Indobufen

Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes[1].

Product Specifications

CAS Number

[63610-08-2]

Product Name Alternative

Ibustrin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/indobufen.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)C(CC)C1=CC=C(N(CC2=C3C=CC=C2)C3=O)C=C1

Molecular Formula

C18H17NO3

Molecular Weight

295.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Eligini S, et al. Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism. Cardiovasc Res. 2006 Jan;69 (1) :218-26.