Indobufen
Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes[1].
Product Specifications
CAS Number
[63610-08-2]
Product Name Alternative
Ibustrin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/indobufen.html
Concentration
10mM
Purity
99.98
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)C(CC)C1=CC=C(N(CC2=C3C=CC=C2)C3=O)C=C1
Molecular Formula
C18H17NO3
Molecular Weight
295.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Eligini S, et al. Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism. Cardiovasc Res. 2006 Jan;69 (1) :218-26.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
COX
Available Sizes
Curated Selection
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