MC-DOXHZN (hydrochloride)
MC-DOXHZN ((E/Z) -Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties[1].
Product Specifications
CAS Number
480998-12-7
Product Name Alternative
(E/Z) -Aldoxorubicin (hydrochloride) ; Doxorubicin (6-maleimidocaproyl) hydrazone (hydrochloride)
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MC-DOXHZN_hydrochloride.html
Purity
98.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[H][C@@]1(O[C@H]2C[C@@](/C(CO)=N\NC(CCCCCN3C(C=CC3=O)=O)=O)(O)CC(C2=C4O)=C(O)C5=C4C(C6=C(OC)C=CC=C6C5=O)=O)O[C@@H](C)[C@@H](O)[C@@H](N)C1.[H]Cl
Molecular Formula
C37H43ClN4O13
Molecular Weight
787.21
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Daunorubicins/Doxorubicins; Topo II
Available Sizes
Frequently Asked Questions
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