Guanabenz (Acetate)
Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
Product Specifications
CAS Number
23256-50-0
Product Name Alternative
BR-750; Wy8678 acetate
UNSPSC
12352005
Hazard Statement
H301
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/Guanabenz-Acetate.html
Concentration
10mM
Purity
98.93
Solubility
DMSO : ≥ 51 mg/mL|H2O : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1.CC(O)=O
Molecular Formula
C10H12Cl2N4O2
Molecular Weight
291.13
Precautions
H301
References & Citations
[1]Walker, B.R., L.E. Hare, and M.W. Deitch, Comparative antihypertensive effects of guanabenz and clonidine. J Int Med Res, 1982. 10 (1) : p. 6-14.|[2]Bonham, A.C., et al., Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine. J Hypertens Suppl, 1984. 2 (3) : p. S543-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
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