Guanabenz (Acetate)

Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.

Product Specifications

CAS Number

[23256-50-0]

Product Name Alternative

BR-750; Wy8678 acetate

UNSPSC

12352005

Hazard Statement

H301

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Guanabenz-Acetate.html

Concentration

10mM

Purity

98.93

Solubility

DMSO : ≥ 51 mg/mL|H2O : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1.CC(O)=O

Molecular Formula

C10H12Cl2N4O2

Molecular Weight

291.13

Precautions

H301

References & Citations

[1]Walker, B.R., L.E. Hare, and M.W. Deitch, Comparative antihypertensive effects of guanabenz and clonidine. J Int Med Res, 1982. 10 (1) : p. 6-14.|[2]Bonham, A.C., et al., Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine. J Hypertens Suppl, 1984. 2 (3) : p. S543-6.