Rac-MF-094

Rac-MF-094 is the racemic mixture of MF-094 (HY-112438) . MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy[1].

Product Specifications

CAS Number

[2758431-95-5]

UNSPSC

12352005

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rac-mf-094.html

Smiles

O=C(C(CC1=CC=CC=C1)NC(C2CCCCC2)=O)NC3=CC=CC4=C(S(=O)(NC(C)(C)C)=O)C=CC=C43

Molecular Formula

C30H37N3O4S

Molecular Weight

535.70

References & Citations

[1]Kluge AF, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28 (15) :2655-2659.