Rac-MF-094
Rac-MF-094 is the racemic mixture of MF-094 (HY-112438) . MF-094 is a potent and selective USP30 inhibitor with an IC50 of 120 nM. MF-094 increases protein ubiquitination and accelerates mitophagy[1].
Product Specifications
CAS Number
[2758431-95-5]
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-mf-094.html
Smiles
O=C(C(CC1=CC=CC=C1)NC(C2CCCCC2)=O)NC3=CC=CC4=C(S(=O)(NC(C)(C)C)=O)C=CC=C43
Molecular Formula
C30H37N3O4S
Molecular Weight
535.70
References & Citations
[1]Kluge AF, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28 (15) :2655-2659.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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