Trans- (S, R, S) -AHPC-Me-Amide-cyclohexane-pyrimidine-Cl
Trans- (S, R, S) -AHPC-Me-Amide-cyclohexane-pyrimidine-Cl is a E3 ligase ligand-linker conjugate, and can be used for synthesis of PROTACs, such as PROTAC BRM/BRG1 degrader-2.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trans-s-r-s-ahpc-me-amide-cyclohexane-pyrimidine-cl.html
Smiles
CC(C)(C)[C@H](NC([C@H](CC1)CC[C@@H]1C2=CN=C(Cl)N=C2)=O)C(N3C[C@H](O)C[C@H]3C(N[C@H](C4=CC=C(C5=C(C)N=CS5)C=C4)C)=O)=O
Molecular Formula
C34H43ClN6O4S
Molecular Weight
667.26
References & Citations
[1]Gu Peng, et al. Brm selective degradation agent compound and use thereof. Patent. WO2023093728
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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