Neocarzilin A
Neocarzilin A (NCA) reduces BST-2 levels via lysosomal degradation. Neocarzilin A has antimigratory and antiproliferative effects on cancer cells. Neocarzilin A inhibits cancer cell migration via irreversible binding to the synaptic vesicle membrane protein VAT-1[1][2].
Product Specifications
CAS Number
124958-29-8
Product Name Alternative
NCA
UNSPSC
12352211
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/neocarzilin-a.html
Purity
95.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC[C@H](C)/C=C/C=C/C=C/C(O)=C/C(C(Cl)(Cl)Cl)=O
Molecular Formula
C14H17Cl3O2
Molecular Weight
323.64
References & Citations
[1]Josef Braun, et al. Neocarzilin Inhibits Cancer Cell Proliferation via BST-2 Degradation, Resulting in Lipid Raft-Trapped EGFR. JACS Au 2024.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2
Available Sizes
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