Human Recombinant CD2 Protein

<strong>Human Recombinant CD2 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2012708_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 34 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> CD2 Recombinant Protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Arulanandam AR, Moingeon P, Concino MF, Recny MA, Kato K, Yagita H, Koyasu S, Reinherz EL. A soluble multimeric recombinant CD2 protein identifies CD48 as a low affinity ligand for human CD2: divergence of CD2 ligands during the evolution of humans and mice J Exp Med. 1993 May 1;177(5):1439-50._x000D_ 2: Drugs R D. 2002;3(1):21-4. doi: 10.2165/00126839-200203010-00004. Alefacept. Amevive, BG 9273, human LFA-3/Igg fusion protein, LFA 3, LFA 3 TIP LFA 3/CD2, LFA-3/Igg fusion protein, LFA3TIP, recombinant LFA-3/Igg1 human fusion protein, recombinantly engineered LFA-1/Igg1 human fusion protein Drugs R D_x000D_ 3: Damschroder MM, Kozhich AA, Woods RM, Cheng L, Mullikin BA, Wilson SD, Ulbrandt ND, Bachy CM, Wu H, Suzich JA, Kiener PA, Dall'Acqua WF, White WI. Analysis of human and primate CD2 molecules by protein sequence and epitope mapping with anti-human CD2 antibodies Mol Immunol. 2004 Aug;41(10):985-1000._x000D_ 4: da Silva AJ, Brickelmaier M, Majeau GR, Li Z, Su L, Hsu YM, Hochman PS. Alefacept, an immunomodulatory recombinant LFA-3/IgG1 fusion protein, induces CD16 signaling and CD2/CD16-dependent apoptosis of CD2(+) cells J Immunol. 2002 May 1;168(9):4462-71._x000D_ 5: Bombil F, Latinne D, Kints JP, Bazin H. Human recombinant interleukin-4 (HurIL-4) improves SCID mouse reconstitution with human peripheral blood lymphocytes Immunobiology. 1996;196(4):437-48._x000D_ 6: Adair BD, Altintas MM, Möller CC, Arnaout MA, Reiser J. Structure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy J Am Soc Nephrol. 2014 Jul;25(7):1465-73._x000D_ 7: Albert-Wolf M, Meuer SC, Wallich R. Dual function of recombinant human CD58: inhibition of T cell adhesion and activation via the CD2 pathway Int Immunol. 1991 Dec;3(12):1335-47._x000D_ 8: Mollereau B, Deckert M, Déas O, Rieux-Laucat F, Hirsch F, Bernard A, Fischer A, Lynch DH, Charpentier B, Le Deist F, Senik A. CD2-induced apoptosis in activated human peripheral T cells: a Fas-independent pathway that requires early protein tyrosine phosphorylation J Immunol. 1996 May 1;156(9):3184-90._x000D_ 9: Lee KA, Kang JW, Shim JH, Kho CW, Park SG, Lee HG, Paik SG, Lim JS, Yoon DY. Protein profiling and identification of modulators regulated by human papillomavirus 16 E7 oncogene in HaCaT keratinocytes by proteomics Gynecol Oncol. 2005 Oct;99(1):142-52._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/7520278">10: van der Merwe PA, Barclay AN, Mason DW, Davies EA, Morgan BP, Tone M, Krishnam AK, Ianelli C, Davis SJ. Human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast dissociation rate but does not bind CD48 or CD59 Biochemistry. 1994 Aug 23;33(33):10149-60. </a>_x000D_ _x000D_ <strong>Products Related to Human Recombinant CD2 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>