Allergin-1, Human (HEK293, His)
Product Specifications
UNSPSC Description
Allergin-1 Protein, an immunoglobulin-like receptor, crucially acts as a negative regulator in mast cells, inhibiting degranulation. Operating as a monomer, it interacts with signaling molecules like tyrosine-phosphorylated PTPN6, PTPN11, and INPP5D, forming complexes that suppress IgE-mediated mast cell activation, thus dampening type I immediate hypersensitivity reactions. Allergin-1 Protein, Human (HEK293, His) is the recombinant human-derived Allergin-1 protein, expressed by HEK293 , with C-His labeled tag.
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/allergin-1-protein-human-hek293-his.html
Purity
96.00
Smiles
RKAVLDCEAM KTNEFPSPCL DSKTKVVMKG QNVSMFCSHK NKSLQITYSL FRRKTHLGTQ DGKGEPAIFN LSITEAHESG PYKCKAQVTS CSKYSRDFSF TIVDPVTSPV LNIMVIQTET DRHITLHCLS VNGSLPINYT FFENHVAISP AISKYDREPA EFNLTKKNPG EEEEYRCEAK NRLPNYATYS HPVTMPSTGG DSCPFCLK
Molecular Weight
Approximately 40-57 kDa due to the glycosylation.
Shipping Conditions
Blue Ice
Storage Conditions
Stored at -20°C for 2 years
Available Sizes
Curated Selection
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