Calcitonin (human)

Calcitonin (human) is a hypocalcemic hormone. Calcitonin can lower blood calcium levels and inhibit bone resorption. Calcitonin can be used in hypercalcemia or osteoporosis research[1][2][3].

Product Specifications

CAS Number

[21215-62-3]

UNSPSC

12352209

Target

CGRP Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/calcitonin-human.html

Purity

99.96

Solubility

DMSO : ≥ 50 mg/mL|H2O : 1.98 mg/mL (ultrasonic; adjust pH to 3 with 1 M HCl)

Smiles

O=C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@H]1[C@H](O)C)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CNC=N5)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC6=CC=CC=C6)C(N7[C@@H](CCC7)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](C(C)C)C(NCC(N[C@@H](C)C(N8[C@@H](CCC8)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC1=O)N

Molecular Formula

C151H226N40O45S3

Molecular Weight

3417.87

References & Citations

[1]Sexton PM, et al. Calcitonin. Current Medicinal Chemistry, 01 Nov 1999, 6 (11) :1067-1093.|[2]Foster GV. Calcitonin. A review of experimental and clinical investigations. Postgrad Med J. 1968 May;44 (511) :411-22.|[3]Bodil-Cecilie Sondergaard, et al. The effect of oral calcitonin on cartilage turnover and surface erosion in an ovariectomized rat model. Arthritis Rheum. 2007 Aug;56 (8) :2674-8.