12 (R) -HETE
12 (R) -HETE is a metabolite of Arachidonic acid, AA and can be found in skin from psoriatic lesions. 12 (R) -HETE induces lymphocytes chemotaxis, stimulates calcium mobilization and chemotaxis in neutrophils via the BLT1 receptor, activates the aryl hydrocarbon receptor, and inhibits Na+/K+ ATPase activity in the corneal epithelium[1][2][3][4].
Product Specifications
CAS Number
82337-46-0
UNSPSC
12352211
Target
Aryl Hydrocarbon Receptor; Na+/K+ ATPase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/12-r-hete.html
Concentration
312.04 μM * 100 μL in Ethanol
Purity
99.90
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C[C@H](/C=C/C=C\C/C=C\CCCC(O)=O)O
Molecular Formula
C20H32O3
Molecular Weight
320.47
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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