Cromakalim
Product Specifications
UNSPSC Description
Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline[1].
Target Antigen
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cromakalim.html
Purity
99.39
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](N2C(CCC2)=O)C3=CC(C#N)=CC=C3OC1(C)C
Molecular Weight
286.331
References & Citations
[1]Cortijo J, et al. The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1992;346(4):462-468.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110011/Cromakalim-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110011/Cromakalim-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
94470-67-4
Available Sizes
Curated Selection
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