Cromakalim
Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline[1].
Product Specifications
CAS Number
94470-67-4
Product Name Alternative
BRL 34915
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cromakalim.html
Purity
99.43
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@@H](N2C(CCC2)=O)C3=CC(C#N)=CC=C3OC1(C)C
Molecular Formula
C16H18N2O3
Molecular Weight
286.33
Precautions
H302, H315, H319
References & Citations
[1]Cortijo J, et al. The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1992;346 (4) :462-468.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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