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Cromakalim

Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline[1].

Product Specifications

CAS Number

[94470-67-4]

Product Name Alternative

BRL 34915

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cromakalim.html

Purity

99.43

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@@H](N2C(CCC2)=O)C3=CC(C#N)=CC=C3OC1(C)C

Molecular Formula

C16H18N2O3

Molecular Weight

286.33

Precautions

H302, H315, H319

References & Citations

[1]Cortijo J, et al. The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1992;346 (4) :462-468.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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