[D-Ala2, Met5]-Enkephalin

<strong>[D-Ala2,Met5]-Enkephalin</strong> <strong>Catalog number:</strong> MDP0489 <strong>CAS Number: </strong>96827-04-2 <strong>Sequence: </strong>Tyr-D-Ala-Gly-Phe-Met . AcOH . H2O <strong>Amount:</strong> 5 mg <strong>Molecular Weight:</strong> 587.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Yeung CW. Radioiodinated [D-Ala2, Met5] enkephalin. Preparation, purification by high performance liquid chromatography and binding characteristics Int J Pept Protein Res. 1984 Dec;24(6):636-44. 2: Yeung CW. Photoreactive enkephalin analogue: [D-Ala2, p-N3-Phe4-Met5]-enkephalin. Synthesis, purification by high performance liquid chromatography and characterization Int J Pept Protein Res. 1985 Jul;26(1):63-9. 3: Ishida T, Yoneda S, Doi M, Inoue M, Kitamura K. Molecular-dynamics simulations of [Met5]- and [D-Ala2,Met5]-enkephalins. Biological implication of monomeric folded and dimeric unfolded conformations Biochem J. 1988 Oct 15;255(2):621-8. 4: Raghubir R, Patnaik GK, Sharma SD, Dhotre BJ, Mathur KB, Dhawan BN. Morphine-like activity of substituted amides & imides of [D-Ala2, Met5]-enkephalin Indian J Med Res. 1989 Apr;90:107-12. 5: Izumi M. [Changes in the potentiation effect of [D-Ala2, Met5]-enkephalin on pressor responses to l-adrenaline in adrenal-enucleated rats] Nihon Yakurigaku Zasshi. 1988 May;91(5):301-8. 6: Stefano GB, Melchiorri P, Negri L, Hughes TK Jr, Scharrer B. [D-Ala2]deltorphin I binding and pharmacological evidence for a special subtype of delta opioid receptor on human and invertebrate immune cells Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9316-20. 7: Yaksh TL, Harty GJ. Effects of thiorphan on the antinociceptive actions of intrathecal [D-Ala2,Met5] enkephalin Eur J Pharmacol. 1982 Apr 23;79(3-4):293-300. 8: Porreca F, Heyman JS, Mosberg HI, Omnaas JR, Vaught JL. Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse J Pharmacol Exp Ther. 1987 May;241(2):393-400. 9: De Simoni MG, Guardabasso V, Misterek K, Algeri S. Similarities and differences between D-ALA2 MET5 enkephalin amide and morphine in the induction of tolerance to their effects on catalepsy and on dopamine metabolism in the rat brain Naunyn Schmiedebergs Arch Pharmacol. 1982 Nov;321(2):105-11. <a href="https://pubmed.ncbi.nlm.nih.gov/6302425">10: Fekete M, Drago F, Van Ree JM, Bohus B, Wiegant VM, De Wied D. Naltrexone-sensitive behavioral actions of the ACTH 4-9 analog (Org 2766) Life Sci. 1983 May 9;32(19):2193-204. </a> <br><strong>Products Related to [D-Ala2,Met5]-Enkephalin can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>