IWP-12
Product Specifications
UNSPSC Description
IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM[1].
Target Antigen
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/iwp-12.html
Purity
99.0
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N=C(N1C)SCC(NC3=NC4=C(S3)C=C(C)C=C4)=O)CC(C)S2
Molecular Weight
418.56
References & Citations
[1]Wang X, et al. The development of highly potent inhibitors for porcupine. J Med Chem. 2013 Mar 28;56(6):2700-4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107570/IWP-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107570/IWP-12-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
688353-45-9
Available Sizes
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