Maribavir

Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV) .

Product Specifications

CAS Number

[176161-24-3]

Product Name Alternative

1263W94; BW1263W94; GW257406X

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

CMV; EBV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Maribavir.html

Purity

99.96

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

ClC1=C(Cl)C=C2C(N=C(NC(C)C)N2[C@@H]3[C@@H](O)[C@@H](O)[C@H](CO)O3)=C1

Molecular Formula

C15H19Cl2N3O4

Molecular Weight

376.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Shannon-Lowe CD, et al. The effects of Maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein. Herpesviridae. 2010 Dec 7;1 (1) :4.|[2]Biron KK, et al. Potent and selective inhibition of human cytomegalovirus replication by 1263W94, a benzimidazole L-riboside with a unique mode of action. Antimicrob Agents Chemother. 2002 Aug;46 (8) :2365-72.