β-Sitostenone

β-Sitostenone is a sterols that can be isolated from Cochlospermum vitifolium.β-Sitostenone inhibits tyrosinase activity, and has anti-melanogenic and anti-tumor activities[1][2][3].

Product Specifications

CAS Number

[1058-61-3]

Product Name Alternative

Δ4-Sitosterol-3-one; β-Rosasterol oxide

UNSPSC

12352211

Target

Endogenous Metabolite; Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/β-sitostenone.html

Purity

95.0

Solubility

DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(CC3)=CC(CC4)=O)C

Molecular Formula

C29H48O

Molecular Weight

412.69

References & Citations

[1]Aguilar-Guadarrama AB, et al. Flavonoids, Sterols and Lignans from Cochlospermum vitifolium and Their Relationship with Its Liver Activity. Molecules. 2018 Aug 5;23 (8) :1952.|[2]Chu CW, et al. Biofunctional Constituents from Michelia compressa var. lanyuensis with Anti-Melanogenic Properties. Molecules. 2015 Jul 3;20 (7) :12166-74.|[3]Fan SQ, et al. Sarocladione, a unique 5,10:8,9-diseco-steroid from the deep-sea-derived fungus Sarocladium kiliense. Org Biomol Chem. 2019 Jun 18;17 (24) :5925-5928.