IR-783
Product Specifications
UNSPSC Description
IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer[1].
Target Antigen
Apoptosis; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Apoptosis;Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ir-783.html
Smiles
O=[S](CCCCN(/C1=C\C=C(CCC2)\C(Cl)=C2/C=C/C(C3(C)C)=[N+](C4=CC=CC=C34)CCCC[S](=O)([O-])=O)C5=CC=CC=C5C1(C)C)(O[Na])=O
Molecular Weight
749.35
References & Citations
[1]Tang Q, et al. Dynamin-related protein 1-mediated mitochondrial fission contributes to IR-783-induced apoptosis in human breast cancer cells. J Cell Mol Med. 2018 Sep;22(9):4474-4485.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139109/IR-783-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139109/IR-783-SDS-MedChemExpress.pdf
CAS Number
115970-66-6
Available Sizes
Curated Selection
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