PFB-FDGlu
PFB-FDGlu is a selective lysosomal Glucocerebrosidase (GCase) substrate, which is metabolised by GCase to yield fluorescein. PFB-FDGlu is cell permeable and can be used with a flow cytometer to measure GCase activity in living cells on a single-cell basis[1].
Product Specifications
CAS Number
[209540-62-5]
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pfb-fdglu.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
OC[C@H]1O[C@@H](OC2=CC3=C(C=C2)C4(C(C=C5)=C(C(O4)=O)C=C5NC(C6=C(C(F)=C(C(F)=C6F)F)F)=O)C7=C(C=C(C=C7)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)O3)[C@H](O)[C@@H](O)[C@@H]1O
Molecular Formula
C39H32F5NO16
Molecular Weight
865.66
References & Citations
[1]Hughes LP, et al. Flow Cytometry Measurement of Glucocerebrosidase Activity in Human Monocytes. Bio Protoc. 2020;10 (7) :e3572.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
039889-APC 200 µL
PEX14, CT (PEX14, Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14) (APC) discontinued
Ask
View Details ![Mouse Monoclonal RPA2 Antibody (OTI9A1) [Janelia Fluor 549]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
MBS6130380-01 0.1 mL
CBLC (Signal Transduction Protein CBL-C, RING Finger Protein 57, SH3-binding Protein CBL-3, SH3-binding Protein CBL-C, CBL3, RNF57) (AP)
Ask
View Details MBS6130380-02 5x 0.1 mL
CBLC (Signal Transduction Protein CBL-C, RING Finger Protein 57, SH3-binding Protein CBL-3, SH3-binding Protein CBL-C, CBL3, RNF57) (AP)
Ask
View Details 
MBS6312361-01 0.2 mL
KCND2, NT (KCND2, KIAA1044, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2) (Azide free) (HRP)
Ask
View Details