Ethyl acetoacetate-d3

Ethyl acetoacetate-d3 is the deuterium labeled Ethyl acetoacetate. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[1][2][3]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[4].

Product Specifications

CAS Number

[1565868-21-4]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Purity

98.0

Solubility

DMSO : 100mg/mL (ultrasonic) |H2O : 100mg/mL (ultrasonic)

Smiles

CCOC(CC(C([2H])([2H])[2H])=O)=O

Molecular Formula

C6H7D3O3

Molecular Weight

133.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Rao M.Uppu, et al. Enantioselective catalytic asymmetric hydrogenation of ethyl acetoacetate in room temperature ionic liquids. Biochemical and Biophysical Research Communications. 1996 Dec; 229 (3) :764-769.|[2]Leo F. Salter, et al. A dual‐frequency Belousov Zhabotinskii oscillating reaction with ethyl acetoacetate as organic substrate. substrate. International Journal of Chemical Kinetics. 1982. 14 (8), 815–821.|[3]Iqbal S, et al. 2-Oxo-1,2,3,4-tetrahydropyrimidines Ethyl Esters as Potent β- Glucuronidase Inhibitors: One-pot Synthesis, In vitro and In silico Studies. Med Chem. 2018;14 (8) :818-830. |[4]Horne SM, et al. Acetoacetate and ethyl acetoacetate as novel inhibitors of bacterial biofilm. Lett Appl Microbiol. 2018 Apr;66 (4) :329-339. |[5]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.