BMS-303141
BMS-303141 is a potent, cell-permeable ATP-citrate lyase (ACL) inhibitor with an IC50 of 0.13 μM.
Product Specifications
CAS Number
[943962-47-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ATP Citrate Lyase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/BMS-303141.html
Purity
99.02
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=S(C1=CC(Cl)=CC(Cl)=C1O)(NC2=CC(C3=CC=CC=C3)=CC=C2OC)=O
Molecular Formula
C19H15Cl2NO4S
Molecular Weight
424.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Li JJ, et al. 2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors. Bioorg Med Chem Lett. 2007 Jun 1;17 (11) :3208-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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