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KRAS G12D ligand-2

KRAS G12D ligand-2 is a Ligand for Target Protein for PROTAC. KRAS G12D ligand-2 can be used to synthesize Setidegrasib (HY-148273) [1].

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/g12d-ligand-1.html

Smiles

[H][C@](C1)(CN2C3=NC(OC4CCOCC4)=NC(C(O)=[C@]5[C@]6=C(C)C(F)=CC7=C6C=NN7)=C3C=C5C8CC8)NC[C@]12[H]

Molecular Formula

C29H31FN6O3

Molecular Weight

530.59

References & Citations

[1]Yoshinari Tomohiro, et al. Quinazoline compound for inducing degradation of g12d-mutation kras protein. WO2022173032A1. 2022 August 18.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

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