KRAS G12D ligand-2
KRAS G12D ligand-2 is a Ligand for Target Protein for PROTAC. KRAS G12D ligand-2 can be used to synthesize Setidegrasib (HY-148273) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/g12d-ligand-1.html
Smiles
[H][C@](C1)(CN2C3=NC(OC4CCOCC4)=NC(C(O)=[C@]5[C@]6=C(C)C(F)=CC7=C6C=NN7)=C3C=C5C8CC8)NC[C@]12[H]
Molecular Formula
C29H31FN6O3
Molecular Weight
530.59
References & Citations
[1]Yoshinari Tomohiro, et al. Quinazoline compound for inducing degradation of g12d-mutation kras protein. WO2022173032A1. 2022 August 18.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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