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N3-PEG4-C2-NHS ester

N3-PEG4-C2-NHS ester is a nonclaevable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG4-C2-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[944251-24-5]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n3-peg4-c2-nhs-ester.html

Purity

98.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN=[N+]=[N-]

Molecular Formula

C15H24N4O8

Molecular Weight

388.37

Precautions

H302, H315, H319, H335

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Non-cleavable Linker

Available Sizes

Curated Selection

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