Serotonin (hydrochloride)
Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
Product Specifications
CAS Number
[153-98-0]
Product Name Alternative
5-Hydroxytryptamine (hydrochloride) ; 5-HT (hydrochloride)
UNSPSC
12352005
Hazard Statement
H301, H361
Target
5-HT Receptor; COMT; Endogenous Metabolite
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Serotonin_hydrochloride.html
Concentration
10mM
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
OC1=CC2=C(NC=C2CCN)C=C1.[H]Cl
Molecular Formula
C10H13ClN2O
Molecular Weight
212.68
Precautions
H301, H361
References & Citations
[1]Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite; Microbial Metabolite; MUC4
Citation 01
Available Sizes
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