WSD0628
Product Specifications
UNSPSC Description
WSD0628 is a brain penetrant and potent ATM inhibitor with profound radiosensitizing effect[1].
Target Antigen
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wsd0628.html
Solubility
10 mM in DMSO
Smiles
CN(C(N1[C@H]2C(F)(F)CN(C)CC2)=O)C3=C1C4=CC(C5=CN=C(OC)C=C5)=CC=C4N=C3
Molecular Weight
439.46
References & Citations
[1]Zhiyi Xue, et al. Abstract A148: The radiosensitizing effects of the novel brain penetrant and potent ATM inhibitor WSD0628 in glioblastoma and melanoma patient derived xenografts. Mol Cancer Ther (2023) 22 (12_Supplement): A148.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162002/WSD0628-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162002/
Clinical Information
Phase 1
CAS Number
2765448-96-0
Available Sizes
Curated Selection
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