WSD0628
WSD0628 is a brain penetrant and potent ATM inhibitor with profound radiosensitizing effect[1].
Product Specifications
CAS Number
2765448-96-0
UNSPSC
12352005
Target
ATM/ATR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wsd0628.html
Purity
99.43
Solubility
10 mM in DMSO
Smiles
CN(C(N1[C@H]2C(F)(F)CN(C)CC2)=O)C3=C1C4=CC(C5=CN=C(OC)C=C5)=CC=C4N=C3
Molecular Formula
C23H23F2N5O2
Molecular Weight
439.46
References & Citations
[1]Zhiyi Xue, et al. Abstract A148: The radiosensitizing effects of the novel brain penetrant and potent ATM inhibitor WSD0628 in glioblastoma and melanoma patient derived xenografts. Mol Cancer Ther (2023) 22 (12_Supplement) : A148.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal EAAT1/GLAST-1/SLC1A3 Antibody [Alexa Fluor 647]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NBP3-05771AF647 0.1 mL
Rabbit Polyclonal EAAT1/GLAST-1/SLC1A3 Antibody [Alexa Fluor 647]
Sign In for Pricing
View Details 
LV762345 1.0 µg DNA
GNPATP Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)
Sign In for Pricing
View Details 
bs-11915R-BF350 100 µL
NRSN1 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated
Sign In for Pricing
View Details 10711071-AAT 500 Tests
IFluor® 532 Anti-human CD71 Antibody *HI166*
Sign In for Pricing
View Details