L-Methionine

L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity[1][2][3].

Product Specifications

CAS Number

[63-68-3]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Endogenous Metabolite; Keap1-Nrf2

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/L-Methionin.html

Purity

99.90

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

N[C@@H](CCSC)C(O)=O

Molecular Formula

C5H11NO2S

Molecular Weight

149.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Benavides MA, et al. L-Methionine inhibits growth of human pancreatic cancer cells. Anticancer Drugs. 2014 Feb;25 (2) :200-3.|[2]Erdmann K, et al. L-methionine reduces oxidant stress in endothelial cells: role of heme oxygenase-1, ferritin, and nitric oxide. AAPS J. 2005 Aug 29;7 (1) :E195-200.|[3]Wang Z, et al. l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats. J Sci Food Agric. 2019 Aug 15;99 (10) :4849-4862.