MT1
MT1 is a bivalent chemical probe of BET bromodomains, with an IC50 of 0.789 nM for BRD4 (1) [1].
Product Specifications
CAS Number
[2060573-82-0]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mt1.html
Purity
99.69
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
CC1=NN=C2N1C3=C(C(C4=CC=C(C=C4)Cl)=N[C@H]2CC(NCCOCCOCCOCCOCCOCCOCCOCCNC(C[C@@H]5N=C(C6=C(N7C5=NN=C7C)SC(C)=C6C)C8=CC=C(C=C8)Cl)=O)=O)C(C)=C(C)S3
Molecular Formula
C54H66Cl2N10O9S2
Molecular Weight
1134.20
References & Citations
[1]Minoru Tanaka, et al. Design and characterization of bivalent BET inhibitors. Nat Chem Biol. 2016 Dec;12 (12) :1089-1096.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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