Nav1.8-IN-11
Nav1.8-IN-11 (Example 1) is a Nav1.8 channel inhibitor with a IC50 value of 0.1 nM. Nav1.8-IN-11 can be used in the study of pain disorders[1].
Product Specifications
CAS Number
2990578-70-4
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nav1-8-in-11.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C=C(C(F)(F)F)C(Cl)=C1C)OC2=CC=C(C3=C2CCC3)F)NC4=CC=C[N+]([O-])=C4
Molecular Formula
C23H17ClF4N2O3
Molecular Weight
480.84
References & Citations
[1]Xuejun Zhang, et al. Nav1.8 inhibitor and use thereof. WO2023186102A1. 2023-10-05.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.8
Frequently Asked Questions
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