EZH2-IN-13
EZH2-IN-13 is a potent EZH2 inhibitor, for details please refer to compound 73 in patent WO2017139404. EZH2-IN-13 can be used to study cancers or precancerous lesions associated with EZH2 activity[1].
Product Specifications
CAS Number
1403255-41-3
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ezh2-in-13.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C2=CC=C(CN3CCNCC3)C=C2)=CC(N(C4CCOCC4)CC)=C1C)NCC5=C(C)C=C(C)NC5=O
Molecular Formula
C34H45N5O3
Molecular Weight
571.75
References & Citations
[1]Jesse Smith, et al. Methods of treating cancer. WO2017139404.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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