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EZH2-IN-13

EZH2-IN-13 is a potent EZH2 inhibitor, for details please refer to compound 73 in patent WO2017139404. EZH2-IN-13 can be used to study cancers or precancerous lesions associated with EZH2 activity[1].

Product Specifications

CAS Number

[1403255-41-3]

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ezh2-in-13.html

Concentration

10mM

Purity

99.72

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(C2=CC=C(CN3CCNCC3)C=C2)=CC(N(C4CCOCC4)CC)=C1C)NCC5=C(C)C=C(C)NC5=O

Molecular Formula

C34H45N5O3

Molecular Weight

571.75

References & Citations

[1]Jesse Smith, et al. Methods of treating cancer. WO2017139404.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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