D-Arabinose-d2
D-Arabinose-d2 is the deuterium labeled D-Arabinose. D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082)[2][3][4][5].
Product Specifications
CAS Number
2419933-20-1
UNSPSC
12352211
Target
AMPK; Bacterial; Isotope-Labeled Compounds; Parasite; PPAR
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease; Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C[C@H]([C@@H]([C@@H](C([2H])([2H])O)O)O)O
Molecular Formula
C5H8D2O5
Molecular Weight
152.14
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
KRT35, CT (KRT35, HHA5, HKA5, KRTHA5, Keratin, type I cuticular Ha5, Hair keratin, type I Ha5, Keratin-35) (MaxLight 550) discontinued
Human Phosphatidylinositol Transfer Protein Beta Isoform (PITPNB) ELISA Kit
Human Phosphatidylinositol Transfer Protein Beta Isoform (PITPNB) ELISA Kit
Human Phosphatidylinositol Transfer Protein Beta Isoform (PITPNB) ELISA Kit