Valproic acid-d7 (sodium)
Valproic acid-d7 (sodium) is the deuterium labeled Valproic acid (sodium salt) . Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].
Product Specifications
CAS Number
1189994-89-5
Product Name Alternative
Sodium Valproate-d7; VPA-d7 (sodium) ; 2-Propylpentanoic acid-d7 (sodium)
UNSPSC
12352211
Hazard Statement
H302-H361
Target
Autophagy; Endogenous Metabolite; HDAC; HIV; Isotope-Labeled Compounds; Mitophagy; Notch
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Stem Cell/Wnt
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
OCCCC(C(O[Na])=O)C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
Molecular Formula
C8H8D7NaO3
Molecular Weight
189.24
Precautions
P202-P264-P280-P301+P312-P308+P313-P405
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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