Lib2-1
Lib2-1, a macrocyclic peptide, is an IL-17C/IL-17RE interaction inhibitor. Lib2-1 can be used for autoimmune and inflammatory diseases research[1].
Product Specifications
CAS Number
[2983116-47-6]
UNSPSC
12352209
Target
Interleukin Related
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lib2-1.html
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC2=CNC=N2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC5=CC=C(C=C5)O)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(NC6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CSC[C@@H](C(NCC(N)=O)=O)NC6=O
Molecular Formula
C81H108N18O23S
Molecular Weight
1733.90
References & Citations
[1]Silong Zhai, et al. PepScaf: Harnessing Machine Learning with In Vitro Selection toward De Novo Macrocyclic Peptides against IL-17C/IL-17RE Interaction. J Med Chem. 2023 Aug 24;66 (16) :11187-11200.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P5963/Lib2-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P5963/Lib2-1-SDS-MedChemExpress.pdf
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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