Foenumoside B

Foenumoside B is a triterpene saponin isolated from Lysimachia foenum-graecum. Foenumoside B activates AMPK signaling, inhibits PPARγ-induced adipogenesis, and shifts lipid metabolism toward lipolysis. Foenumoside B can be used in the study of obesity and obesity-related metabolic diseases[1].

Product Specifications

CAS Number

[877661-00-2]

UNSPSC

12352005

Target

AMPK; PPAR

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/foenumoside-b.html

Solubility

10 mM in DMSO

Smiles

CC(OC[C@]12[C@](CC(C)([C@H]([C@@H]2O)OC(/C(C)=C\C)=O)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@H](CC4)O[C@H]5[C@@H]([C@H]([C@H](CO5)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)C)([H])CC9)C)([H])[C@]9(C)[C@@]3(C[C@H]1O)C)=O

Molecular Formula

C60H96O25

Molecular Weight

1217.39

References & Citations

[1]Seo JB, et al. Foenumoside B from Lysimachia foenum-graecum inhibits adipocyte differentiation and obesity induced by high-fat diet. Biochem Biophys Res Commun. 2012 Jan 13;417 (2) :800-6.