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Bergapten

Product Specifications

UNSPSC Description

Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms.

Target Antigen

Autophagy; Cytochrome P450

Type

Natural Products

Related Pathways

Autophagy;Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-Methoxypsoralen.html

Purity

99.96

Solubility

DMSO : 20 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)

Smiles

O=C1C=CC2=C(OC)C3=C(OC=C3)C=C2O1

Molecular Weight

216.19

References & Citations

[1]Lee YM, et al. Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In Vivo. 2005 Nov-Dec;19(6):1061-9.|[2]Li XJ, et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice. Int J Mol Med. 2016 Dec;38(6):1661-1672.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0370/Bergapten-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0370/Bergapten-SDS-MedChemExpress.pdf

Clinical Information

Phase 3

CAS Number

484-20-8

Available Sizes

Curated Selection

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