Bergapten
Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms.
Product Specifications
CAS Number
[484-20-8]
Product Name Alternative
5-Methoxypsoralen
UNSPSC
12352005
Hazard Statement
H317
Target
Autophagy; Cytochrome P450
Type
Natural Products
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-Methoxypsoralen.html
Purity
99.96
Solubility
DMSO : 20 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=C(OC)C3=C(OC=C3)C=C2O1
Molecular Formula
C12H8O4
Molecular Weight
216.19
Precautions
H317
References & Citations
[1]Lee YM, et al. Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In Vivo. 2005 Nov-Dec;19 (6) :1061-9.|[2]Li XJ, et al. Bergapten exerts inhibitory effects on diabetes-related osteoporosis via the regulation of the PI3K/AKT, JNK/MAPK and NF-κB signaling pathways in osteoprotegerin knockout mice. Int J Mol Med. 2016 Dec;38 (6) :1661-1672.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 3
Available Sizes
Curated Selection
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