RIPK1-IN-10
RIPK1-IN-10 is a potent RIPK1 inhibitor, example 37, extracted from patent WO2021160109[1].
Product Specifications
CAS Number
[2682889-51-4]
UNSPSC
12352005
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ripk1-in-10.html
Concentration
10mM
Purity
98.25
Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=C(C1CC1)NC2=CN3N=C(C4=CC5=C(N=C4)CCN(CC6=CC(F)=CC(F)=C6OC7CCOCC7)C5=O)C=CC3=N2
Molecular Formula
C30H28F2N6O4
Molecular Weight
574.58
References & Citations
[1]Zhou FuSheng, et al. Dihydronaphthyridinone compound, and preparation method therefor and medical use thereof. Patent WO2021160109.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RIPK1
Available Sizes
Curated Selection
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