RIPK1-IN-10

RIPK1-IN-10 is a potent RIPK1 inhibitor, example 37, extracted from patent WO2021160109[1].

Product Specifications

CAS Number

[2682889-51-4]

UNSPSC

12352005

Target

RIP kinase

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ripk1-in-10.html

Concentration

10mM

Purity

98.25

Solubility

DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 70°C)

Smiles

O=C(C1CC1)NC2=CN3N=C(C4=CC5=C(N=C4)CCN(CC6=CC(F)=CC(F)=C6OC7CCOCC7)C5=O)C=CC3=N2

Molecular Formula

C30H28F2N6O4

Molecular Weight

574.58

References & Citations

[1]Zhou FuSheng, et al. Dihydronaphthyridinone compound, and preparation method therefor and medical use thereof. Patent WO2021160109.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RIPK1

Available Sizes

Curated Selection

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