PF-07054894
PF-07054894 is an orally active and potent C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) antagonist that blocks CCR6-mediated chemotaxis with an IC50 value of 5.7 nM in vitro. PF-07054894 targets G protein-coupled receptor (GPCR) . PF-07054894 can be used in research of inflammatory bowel disease[1][2][3][4].
Product Specifications
CAS Number
2413693-96-4
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pf-07054894.html
Concentration
10mM
Purity
99.15
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C(C(N(C)C)=O)N=CC=C1NC2=C(N[C@@H](C3=NN(C)C=C3C)C4(C)CCCC4)C(C2=O)=O
Molecular Formula
C24H30N6O4
Molecular Weight
466.53
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
CCR6
Available Sizes
Frequently Asked Questions
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