Resorufin

Resorufin (NSC 12097) is a highly fluorescent pink dye. Resorufin shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin is used for the detection of ROS/RNS and a second analyte[1][2].

Product Specifications

CAS Number

[635-78-9]

Product Name Alternative

NSC 12097

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye; Reactive Oxygen Species (ROS)

Type

Dye Reagents

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Resorufin.html

Purity

99.0

Solubility

0.5 M NaOH : 4.38 mg/mL (ultrasonic; warming; adjust pH to 13 with 0.5 M NaOH; heat to 60°C) |DMSO : < 1 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic)

Smiles

O=C1C=CC2=NC3=C(OC2=C1)C=C(C=C3)O

Molecular Formula

C12H7NO3

Molecular Weight

213.19

Precautions

H315, H319, H335

References & Citations

[1]Odyniec ML , et al. 'AND'-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb) . 2018 Jul 26;54 (61) :8466-8469.|[2]Almammadov T, et al. Resorufin Enters the Photodynamic Therapy Arena: A Monoamine Oxidase Activatable Agent for Selective Cytotoxicity. ACS Med Chem Lett. 2020 Nov 23;11 (12) :2491-2496.