IL-17RA, Rat (HEK293, His)

Product Specifications

UNSPSC Description

IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F[1][2]. IL-17RA Protein, Rat (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 320 amino acids (M1-P320).

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-17ra-protein-rat-hek293-his.html

Purity

95.0

Smiles

SLRLLDFPAL VCSQEGLNCR VENSTCLDDS WIYPRNLTPS SPKNIYLHLN VSSTQHGDLV PVLHVEWTLQ TDASILYLEG AELSILKLNT NEQLCVKFKF LSKLSNHHKR WRFSFSHFVV DPGQEYEVTV HHLPKPIPDG DPNHKSKTIL VPGCEDTEMK MTTPCVSSGS LWNPNITVET LDTQHLRVDF TLWNESTPYQ ILLESFSGSE NQSCFEDIKQ ISAPGQEEFH QRSNVTFTLS KSGWCCHHLV QVQPFFNSCQ NDCLRHAVTV PCPVISETPV SITAADYIP

Molecular Weight

52-58 kDa

References & Citations

[1]Stéphane Nesmond, et al. Characteristic Pattern of IL-17RA, IL-17RB, and IL-17RC in Monocytes/Macrophages and Mast Cells From Patients With Bullous Pemphigoid. Front Immunol. 2019 Sep 11;10:2107.|[2]Xun Lin, et al. IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. 2022 Feb 8;55(2):237-253.e8.|[3]Laura Green, et al. Chronic Candidiasis in Children. Curr Allergy Asthma Rep. 2017 May;17(5):31.