A-71915 (TFA)
Product Specifications
UNSPSC Description
A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells[1].
Target Antigen
Apoptosis
Type
Peptides
Related Pathways
Apoptosis
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/a-71915-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CCCNC(N)=N)N[C@H](C(N[C@H](C(NCC(NCC(N[C@@H](C(C[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C([N]1=CC2=C(C=C13)C=CC=C2)=O)[C@@H](CC)C)=O)CCCNC(N)=N)=O)CC(O)=O)=O)[C@@H](CC)C)=O)CCCNC(N)=N)=O)=O)=O)CC4CCCCC4)=O)CSSC[C@@H](NC([C@H](NC3=O)CCCNC(N)=N)=O)C(N)=O.OC(C(F)(F)F)=O
Molecular Weight
1727.98
References & Citations
[1]Wong JC, et al. Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1. Diab Vasc Dis Res. 2017 Sep;14(5):434-449.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1980/A-71915-TFA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1980/
Clinical Information
No Development Reported
Curated Selection
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