Citrulline-specific probe-rhodamine (hydrate)
Product Specifications
UNSPSC Description
Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis[1].
Target Antigen
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/citrulline-specific-probe-rhodamine-hydrate.html
Solubility
10 mM in DMSO
Smiles
O=CC(C1=CC(NC(C(C)N2N=NC(CNC(C3=CC=C4C(C(OC45C6=CC=C(N(C)C)C=C6OC7=CC(N(C)C)=CC=C75)=O)=C3)=O)=C2)=O)=CC=C1)=O.O
Molecular Weight
731.75
References & Citations
[1]Bicker K L, Subramanian V, Chumanevich A A, et al. Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination[J]. Journal of the American Chemical Society, 2012, 134(41): 17015-17018.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D1377/Citrulline-specific-probe-rhodamine-hydrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D1377/
Clinical Information
No Development Reported
CAS Number
2309313-01-5
Available Sizes
Curated Selection
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