O-Phenanthroline (monohydrate)

O-Phenanthroline (1,10-Phenanthroline) monohydrate, a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) monohydrate is also a MMP inhibitor[1][2].

Product Specifications

CAS Number

[5144-89-8]

Product Name Alternative

1,10-Phenanthroline (monohydrate)

UNSPSC

12352200

Hazard Statement

H301, H410

Target

MMP

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/o-phenanthroline-monohydrate.html

Concentration

10mM

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C12=C(N=CC=C3)C3=CC=C1C=CC=N2.O

Molecular Formula

C12H10N2O

Molecular Weight

198.22

Precautions

H301, H410

References & Citations

[1]Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68.|[2]Zi-Qiang Liu, et al. The role of matrix metalloprotease (MMP) to the autolysis of sea cucumber (Stichopus japonicus) . J Sci Food Agric. 2019 Oct;99 (13) :5752-5759.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature, keep dry and cool

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Citation 01

Nat Commun. 2023 May 2;14 (1) :2523.|Adv Sci (Weinh) . 2025 Aug 30:e09817.|Ind Crops Prod. 2024 Sep 1, 215, 118652.|Mol Cell. 2023 Nov 16;83 (22) :4000-4016.e6.