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Ropidoxuridine

Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors.

Product Specifications

CAS Number

[93265-81-7]

Product Name Alternative

IPdR

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H315, H319, H341, H361

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Ropidoxuridine.html

Purity

99.59

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C1N=CC(I)=CN1[C@H]2C[C@H](O)[C@@H](CO)O2

Molecular Formula

C9H11IN2O4

Molecular Weight

338.10

Precautions

H302+H312+H332, H315, H319, H341, H361

References & Citations

[1]Rampurwala MM, et al. Ropidoxuridine (IPdR) potentiates alisertib (MLN8237) activity in triple-negative breast cancer. [abstract]. In: Proceedings of the Thirty-Eighth Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2015 Dec 8-12; San Antonio, TX. Philadelphia (PA) : AACR; Cancer Res 2016;76 (4 Suppl) :Abstract nr P6-13-16.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Curated Selection

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