Glycyrrhetic acid 3-O-β-D-glucuronide

Glycyrrhetic acid 3-O-β-D-glucuronide, isolated from glycyrrhiza, is an important derivative of glycyrrhizin (GL) with an anti -allergic activity[1]. Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) shows that β-glucuronidases (β-GUS) are key GAMG-producing enzymes, displaying a high potential to convert GL directly into GAMG[2].Glycyrrhetic acid 3-O-β-D-glucuronide is valuable as a sweetener.

Product Specifications

CAS Number

[34096-83-8]

Product Name Alternative

Glycyrrhetic acid 3-O-mono-β-D-glucuronide; 3-monoglucuronyl-glycyrrhetinic acid

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/glycyrrhetic-acid-3-o-beta-d-glucuronide.html

Purity

99.59

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

C[C@@]1([C@@]2([H])[C@@]3([C@@](C(C)([C@@H](O[C@]4([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)CC3)C)([H])CC1)C)[C@]5(C([C@@]6([H])[C@](C)(CC[C@@](C(O)=O)(C)C6)CC5)=CC2=O)C

Molecular Formula

C36H54O10

Molecular Weight

646.81

References & Citations

[1]Park HY, et al. Anti-allergic activity of 18beta-glycyrrhetinic acid-3-O-beta-D-glucuronide.Arch Pharm Res. 2004 Jan;27 (1) :57-60.|[2]Lichun Guo, et al. Glycyrrhetic Acid 3‐O‐Mono‐β‐d‐glucuronide (GAMG) : An Innovative High‐Potency Sweetener with Improved Biological Activities. Comprehensive Reviews in Food Science and Food Safety