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GSK3β inhibitor II

GSK3β inhibitor II is an inhibitor of GSK3β. GSK3β inhibitor II can be used for research of Alzheimer’s disease (AD) [1].

Product Specifications

CAS Number

[478482-75-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

GSK-3

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/gsk3β-inhibitor-ii.html

Purity

99.49

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

IC1=CC=CC(CSC(O2)=NN=C2C3=CC=NC=C3)=C1

Molecular Formula

C14H10IN3OS

Molecular Weight

395.22

Precautions

H302, H315, H319

References & Citations

[1]Elangovan ND, et al. Screening of potential drug for Alzheimer's disease: a computational study with GSK-3 β inhibition through virtual screening, docking, and molecular dynamics simulation. J Biomol Struct Dyn. 2021 Nov;39 (18) :7065-7079.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GSK-3β

Available Sizes

Curated Selection

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